Difficulty expressing wants and needs can result in embarrassment, frustration, isolation, and depression. Other problems may occur together such as more difficulty moving around and problems with memory and thinking.
Tuesday, 21 June 2022
Aphasia (inability (or impaired ability))
Difficulty expressing wants and needs can result in embarrassment, frustration, isolation, and depression. Other problems may occur together such as more difficulty moving around and problems with memory and thinking.
Wednesday, 25 May 2022
Monkeypox
Thursday, 19 May 2022
Fibromyalgia
Fibromyalgia
Fibromyalgia is a disorder characterized by widespread musculoskeletal pain accompanied by fatigue, sleep, memory, and mood issues. Researchers believe that fibromyalgia amplifies painful sensations by affecting the way your brain and spinal cord process painful and non-painful signals.
Symptoms often begin after an event, such as physical trauma, surgery, infection, or significant psychological stress. In other cases, symptoms gradually accumulate over time with no single triggering event.
Women are more likely to develop fibromyalgia than men. Many people who have fibromyalgia also have tension headaches, temporomandibular joint disorders, irritable bowel syndrome, anxiety, and depression.
Symptoms:
The primary symptoms of fibromyalgia include:
- Widerspread pain: The pain associated with fibromyalgia often is described as a constant dull ache that has lasted for at least three months. To be considered widespread, the pain must occur on both sides of your body and above and below your waist.
- Fatigue: People with fibromyalgia often awaken tired, even though they report sleeping for long periods of time. Sleep is often disrupted by pain, and many patients with fibromyalgia have other sleep disorders, such as restless legs syndrome and sleep apnea.
Cognitive difficulties: A symptom commonly referred to as "Fibro fog" impairs the ability to focus, pay attention and concentrate on mental tasks.
Co-exists condition with fibromyalgia:
- Irritable bowel syndrome
- Chronic fatigue syndrome
- Migraine and other types of headaches
- Interstitial cystitis or painful bladder syndrome
- Temporomandibular joint disorders
- Anxiety
- Depression
- Postural tachycardia syndrome
People may experience:
Pain areas: In the muscles, abdomen, back, or neck
Pain types: Can be chronic, diffuse, sharp, or severe
Pain circumstances: can occur at night
Whole-body: fatigue, feeling tried, or malaise
Muscular: Muscle tenderness, delayed onset muscle soreness, or muscle spams
Gastrointestinal: constipation, nausea, or passing excessive amounts of gas
Mood: anxiety mood swings or nervousness
Cognitive: forgetfulness or lack of concentration
Hand: the sensation of coldness or tingling
Sensory: pins and needles or sensitivity to pain
Sleep: difficulty falling asleep or sleep disturbances
Also common: Depression, flare, headache, irritability, joint stiffness, painful menstruation, sensitivity to cold, or tingling feet.
Causes:
Many researchers believe that repeated nerve stimulation causes the brain and spinal cord of people with fibromyalgia to change. This change involves an abnormal increase in levels of certain chemicals in the brain that signal pain. In addition, the brain's pain receptors seem to develop a sort of memory of the pain and become sensitized, meaning they can overreact to painful and nonpainful signals. Here are likely many factors that lead to these changes, including:
Genetics: Because fibromyalgia tends to run in families, there may be certain genetic mutations that may make you more susceptible to developing the disorder.
Infections: some illnesses appear to trigger or aggravate fibromyalgia.
physical or emotional event: Fibromyalgia can sometimes be triggered by a physical event, such as a car accident. Prolonged psychological stress may also trigger the condition.
Risk factors: Risk factors for fibromyalgia include:
Sex: Fibromyalgia is diagnosed more often in women than in men.
Family history: You may be more likely to develop fibromyalgia if a parent or sibling also has the condition.
Other disorders: If you have osteoarthritis, rheumatoid arthritis, or lupus, you may be more likely to develop fibromyalgia.
Complication:
The pain, fatigue, and poor sleep quality associated with fibromyalgia can interfere with your ability to function at home or on the job. The frustration of dealing with an often-misunderstood condition also can result in depression and health-related anxiety.
Diagnosis:
In the past, doctors would check 18 specific points on a person's body to see how many of them were painful when pressed firmly. Newer guidelines from the American College of Rheumatology don't require a tender point exam. Instead, the main factor needed for a fibromyalgia diagnosis is widespread pain throughout your body for at least three months.
To meet the criteria, you must have pain in at least four of these five areas:
- Left upper region: Including shoulder, arm, or jaw
- Right upper region, including shoulder, arm, or jaw
- Left lower region: Including hip, buttock, or leg
- Right lower region: Including hip, buttock, or leg
Axial region: This includes the neck, back, chest, or abdomen.
Tests:
The doctor may want to rule out other conditions that may have similar symptoms. blood tests may include:
- Complete blood count (CBC)
- Erythrocyte sedimentation rate
- Cyclic citrullinate peptide test
- Rheumatoid factor
- Thyroid function tests
- Anti-nuclear antibody
- Celiac serology
- vitamin D
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Saturday, 2 April 2022
Dravet Syndrome
Dravet Syndrome
Dravet syndrome is a severe form of epilepsy characterized by frequent, prolonged seizures often triggered by high body temperature (hyperthermia), developmental delay, speech impairment, ataxia, hypotonia, sleep disturbances, and other health problems.
What is the life expectancy of a child with Dravet syndrome?
The average life expectancy of people with Dravet syndrome is not clear, but estimates suggest that 10-20% of individuals with a sudden unexpected death in epilepsy is the most common cause.
Dravet syndrome, previously known as severe myoclonic epilepsy in infancy, is a rare form of epilepsy that begins in the first year of life.
Estimates suggest it affects around 1 in 40,000 trusted source infants in the united states, though some studies indicate its true incidence may be closer to 1 in 15,000.
As well as seizures, common symptoms include mobility, behavioral, and cognitive abnormalities that develop as the child gets older.
While there is no cure for Dravet syndrome, early diagnosis and treatment may minimize seizure frequency and intensity. Without treatment, individuals will continue to have frequent seizures and can suffer from seizure-related accidents or even mortality.
Keep reading to learn more about Dravet syndrome, including the causes, symptoms, and treatment options for the condition.
Causes:
The cause of Dravet syndrome is a gene mutation. Dravet syndrome most often results from a do Novo variation, a genetic mutation not present in a child's parents. It typically develops for the first in the egg, sperm, or early embryo.
In 70-80% of individuals with Dravet syndrome, the mutation is in the SCN1A gene, which provides instructions for creating sodium channels found primarily in the brain. These channels control the flow of sodium ions and affect communication between nerve cells or neurons.
Researches suggest that SCN1A gene mutations may result in trusted source uncontrolled firing from gamma-aminobutyric acid functions as the primary inhibitory neurotransmitter for the central nervous system. Dravet syndrome appears to affect males twice as often as it affects females.
Symptoms:
Symptoms of Dravet syndrome vary by person and often change as the individual gets older. The three most commonly associated symptoms with this condition are seizures, developmental delays, and behavioral abnormalities.
Seizures:
Most individuals with Dravet syndrome start to have seizures at the age of 5-8 months trusted sources. The first seizure usually results from a trigger like a fever, but sometimes there is no trigger.
When a fever triggers a seizure, this is called a febrile seizure. Many infants have febrile seizures, and these symptoms alone don't mean a baby has Dravet syndrome.
Individuals with Dravet syndrome typically also develop other types of seizures, including:
- Focal seizures which occur in one area of the brain
- Myoclonic seizure, which causes the upper body or legs to jerk of twitch
- Atypical absence seizures which cause lapses of consciousness that can last for 20 seconds or longer
- Tonic-clonic seizures make the whole body twitch and jerk and cause a person to become unconscious.
Individuals with Dravet syndrome can get a seizure when they experience stress, and excitement, see flashing lights or have a rapid change in body temperature.
Developmental delay:
Parents typically begin to notice cognitive delays or difficulty learning and talking in infants with Dravet syndrome at 1-2 years. It can take these infants longer to reach certain milestones compared with other children.
Hypotonia, a lack of muscle tone, is common in individuals with Dravet syndrome at around 1 year old. Parents may also notice signs of ataxia, a disorder that affects coordination and balance when infants start walking.
Behavioral disturbances:
The behavioral traits associated with Dravet syndrome relate to autism, attention deficit hyperactivity disorder, irritability, and aggression.
Diagnosis:
Dravet syndrome is rare and can be challenging for doctors to diagnose. According to the international league against epilepsy trusted source, a doctor generally uses the following characteristics of the trusted sources to make a diagnosis:
- A family history of seizures or febrile seizures
- Normal developmental before the onset of seizures
- A seizure during the first year of life, followed by an increasing number of various seizures types
- An EEG test with generalized spike and polyspike waves
- Focal abnormalities or early photosensitivity
- Psychomotor delays after the age of 24 months
- Ataxia
Doctors typically recommend genetic testing in individuals likely to have Dravet syndrome.
Diet:
Research suggests that Ketogenic which is high in fat and low in carbohydrates, may help individuals with Dravet syndrome, the diet affects biochemical pathways involved in the functioning of the central nervous system. It also affects GABA levels.
Avoiding triggers:
Avoiding seizure triggers is important for people with Dravet syndrome. Hot baths, Jacuzzis, and flashing lights can all bring on seizures.